1-Iodopropane → HCID 22397833, compound

HRID 1483891Notes

Reaction equation

HRID 1483891 reaction equation
[N:1]1([C:7]2[CH:8]=[C:9]([C:13](=[O:15])[CH3:14])[CH:10]=[CH:11][CH:12]=2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[CH2:16](I)[CH2:17][CH3:18].C([O-])(=O)C([O-])=O>CCOC(C)=O>[CH2:16]([N:4]1[CH2:5][CH2:6][N:1]([C:7]2[CH:8]=[C:9]([C:13](=[O:15])[CH3:14])[CH:10]=[CH:11][CH:12]=2)[CH2:2][CH2:3]1)[CH2:17][CH3:18]

Participants

5

Reactant 3

HCID 336431-IodopropaneHCID 71081OxalateHCID 22031745HCID 22031745, compound

Product 1

HCID 22397833HCID 22397833, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Beginning with 1-(3-Piperazin-1-yl-phenyl)-ethanone and n-Pr-I: m.p. 119° C. (oxalate), MS m/z (rel. intensity, 70 eV) 246 (M+, 10), 217 (33), 132 (18), 70 (bp), 56 (41); Rf 0.23 (EtOAc).

Sources & evidence

ORD record
ord-bf1787e719dc40daba79718147c652b8
Source dataset
uspto-grants-2016_08
Patent number
USRE046117E1

Reaction notes

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