4-Aminopyridine → Carbamic acid, 4-pyridinyl-, 4-nitrophenyl ester

HRID 1483974Notes

Reaction equation

HRID 1483974 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([NH2:7])=[CH:3][CH:2]=1.Cl[C:9]([O:11][C:12]1[CH:17]=[CH:16][C:15]([N+:18]([O-:20])=[O:19])=[CH:14][CH:13]=1)=[O:10]>>[N:1]1[CH:6]=[CH:5][C:4]([NH:7][C:9](=[O:10])[O:11][C:12]2[CH:13]=[CH:14][C:15]([N+:18]([O-:20])=[O:19])=[CH:16][CH:17]=2)=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 17274-AminopyridineHCID 821294-Nitrophenyl chloroformate

Product 1

HCID 10355188Carbamic acid, 4-pyridinyl-, 4-nitrophenyl ester

Procedure

Prepared as Example 27d from pyridin-4-amine and p-nitrophenyl chloroformate to provide the compound as an off white solid. MS=260 (MH+).

Workup

  1. customto provide the compound as an off white solid

Sources & evidence

ORD record
ord-c3e76c6df30f4cf085373821eb03a36d
Source dataset
uspto-grants-2016_08
Patent number
US09420814B2

Reaction notes

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