Dimethylformamide → Tert-butyl trans-4-(4-chlorocarbonylphenyl)cyclohexaneacetate

HRID 148817Notes

Reaction equation

HRID 148817 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[CH2:8][CH:9]1[CH2:10][CH2:11][CH:12]([c:15]2[cH:16][cH:17][c:18]([C:19](=[O:20])[OH:21])[cH:22][cH:23]2)[CH2:13][CH2:14]1.[CH3:30][N:31]([CH3:32])[CH:33]=[O:34].[Cl:24][C:25]([C:26]([Cl:27])=[O:28])=[O:29].[Cl:35][CH2:36][Cl:37]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[CH2:8][CH:9]1[CH2:10][CH2:11][CH:12]([c:15]2[cH:16][cH:17][c:18]([C:19](=[O:20])[Cl:24])[cH:22][cH:23]2)[CH2:13][CH2:14]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 65578Oxalyl chlorideHCID 666854144-(4-Tert-butoxycarbonylmethylcyclohexyl)benzoic acid

Product 1

HCID 86662118Tert-butyl trans-4-(4-chlorocarbonylphenyl)cyclohexaneacetate

Sources & evidence

ORD record
ord-485ac87f84e64a4f9a5bf145882b6f62
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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