Ethyl 4-benzyloxyphenethyl sulfonate → Ethyl 4-hydroxyphenethyl sulfonate

HRID 1488339Notes

Reaction equation

HRID 1488339 reaction equation
C([O:8][C:9]1[CH:22]=[CH:21][C:12]([CH2:13][CH2:14][S:15]([O:18][CH2:19][CH3:20])(=[O:17])=[O:16])=[CH:11][CH:10]=1)C1C=CC=CC=1.[H][H]>C(OCC)(=O)C.[Pd]>[OH:8][C:9]1[CH:22]=[CH:21][C:12]([CH2:13][CH2:14][S:15]([O:18][CH2:19][CH3:20])(=[O:17])=[O:16])=[CH:11][CH:10]=1

Participants

5

Reactant 2

HCID 22904628Ethyl 4-benzyloxyphenethyl sulfonateHCID 178418361HCID 178418361, compound

Product 1

HCID 22904632Ethyl 4-hydroxyphenethyl sulfonate

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

To a solution of ethyl 4-benzyloxyphenethyl sulfonate (1.43 g) in ethyl acetate (25 ml) is added 10% palladium on carbon (0.25 g) and the mixture shaken under 30 psi of hydrogen for 3 hours. The mixture is filtered and concentrated in vacuo to give ethyl 4-hydroxyphenethyl sulfonate.

Workup

  1. filtrationThe mixture is filtered
  2. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-8aabc9ad8e5c4f8889a411bd917c1cb5
Source dataset
uspto-grants-1997_10
Patent number
US05674482

Reaction notes

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