反应详情

To a stirred slurry of 2-(2,4-di-t-butyl phenoxy) propionic acid (27.8 g, 0.100 mol) in CH2Cl2 (280 mL) with 2 mL of DMF, oxalyl chloride (17.0 g, 0.134 mol) was added dropwise. The solution resulted after several minutes was stirred for 2 hr. TLC indicates no starting material. The solution was filtered through a glass wool plug to remove some debris and the filtrate was concentrated in vacuo, residue was washed with CH2Cl2 (50 mL) and was concentrated once more to give a gelatinous mixture, which was used without further purification.

1. customThe solution resulted after several minutes
2. filtrationThe solution was filtered through a glass wool plug
3. customto remove some debris
4. concentrationthe filtrate was concentrated in vacuo, residue
5. washwas washed with CH2Cl2 (50 mL)
6. concentrationwas concentrated once more
7. customto give a gelatinous mixture, which
8. customwas used without further purification