Hydrochloric Acid → HCID 22903575, compound

HRID 1488962Notes

Reaction equation

HRID 1488962 reaction equation
[Cl:1][C:2]1[CH:8]=[C:7]([N+:9]([O-])=O)[C:5]([NH2:6])=[CH:4][C:3]=1[N:12]1[CH:17]=[CH:16][C:15](=[O:18])[CH:14]=[CH:13]1.O.Cl>[Fe].C(O)C>[Cl:1][C:2]1[C:3]([N:12]2[CH:17]=[CH:16][C:15](=[O:18])[CH:14]=[CH:13]2)=[CH:4][C:5]([NH2:6])=[C:7]([NH2:9])[CH:8]=1

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 962WaterHCID 22903586HCID 22903586, compound

Product 1

HCID 22903575HCID 22903575, compound

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 702EthanolSolvent2×

Procedure

First, a mixture containing 3.0 g of 4-chloro-3-(4-oxo-4H-pyridin-1-yl)-6-nitroaniline, 3.78 g of iron powder, 10 ml of water, 90 ml of ethanol, and 1.15 ml of 2N hydrochloric acid was refluxed by heating in an oil bath for 3 hours. Then, 135 ml of ethanol was added to the mixture, and insoluble substances were filtered with Hyflo Super-Cel (trade name) and the solvent was removed.

Workup

  1. temperaturewas refluxed
  2. temperatureby heating in an oil bath for 3 hours
  3. filtrationwere filtered with Hyflo Super-Cel (trade name)
  4. customthe solvent was removed

Sources & evidence

ORD record
ord-e0c655ed26b842b8bb9221f588387aa8
Source dataset
uspto-grants-1997_10
Patent number
US05677305

Reaction notes

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