Guanidine → HCID 178466832, compound

HRID 1489799Notes

Reaction equation

[C:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][C:12]=1[OH:13])[C:7](O)=[O:8])(=[O:3])[CH3:2].C(N1C=CN=C1)(N1C=CN=C1)=O.[NH2:26][C:27]([NH2:29])=[NH:28]>>[C:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][C:12]=1[OH:13])[C:7]([NH:28][C:27]([NH2:29])=[NH:26])=[O:8])(=[O:3])[CH3:2]

Participants

Reactant 3

HCID 3520Guanidine

HCID 682631,1'-Carbonyldiimidazole

HCID 91792453-Acetyl-4-hydroxybenzoic acid

Product 1

HCID 178466832HCID 178466832, compound

Procedure

1.0 eq. of 3-acetyl-4-hydroxybenzoic acid was reacted in accordance with Variant A with 1.1 eq. of carbonyldiimidazole and 5 eq. of guanidine. Colorless crystals, mp 218°-221° C.

Sources & evidence

ORD record: ord-fd5b68a65c504e46a9aceec9027a5ec1
Source dataset: uspto-grants-1997_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05679712

Reaction notes

Loading…