4-Cyanoindole → 1219637-83-8

HRID 1490422Notes

Reaction equation

HRID 1490422 reaction equation
N#Cc1cccc2[nH]ccc12>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.CC(C)(C)c1ccnc(-c2cc(C(C)(C)C)ccn2)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CC1(C)OBOC1(C)C.[Cl-].[Cl-].[Ir].[Ir]>CC1(C)OB(c2ccc(C#N)c3cc[nH]c23)OC1(C)C

Participants

7

Reactant 1

HCID 38176024-Cyanoindole

Product 1

HCID 461918241219637-83-8Yield 49%

Reagents, catalysts & solvents 5

HCID 2733548Bis(pinacolato)diboraneReagentHCID 27347684,4,5,5-Tetramethyl[1,3,2]dioxaborolaneReagentHCID 42491874,4'-Di-tert-butyl-2,2'-bipyridylReagentHCID 82923Chloro-1,5-cyclooctadiene-iridium(I) dimerCatalystHCID 8028TetrahydrofuranSolvent

Conditions

Temperature
80 °C

Sources & evidence

ORD record
ord-8a61838e78a84891a83b90ff3136bf2a
Source dataset
Borylation dataset from Roche

Reaction notes

Loading…