N,N-Dimethylaniline → N,N-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

HRID 1490488Notes

Reaction equation

HRID 1490488 reaction equation
CN(C)c1ccccc1>B1Oc2ccccc2O1.CC(C)(O)C(C)(C)O.CCN(CC)CC.Cc1ccccc1.Fc1c(F)c(F)c(B(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F>CN(C)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1

Participants

7

Reactant 1

HCID 949N,N-Dimethylaniline

Product 1

HCID 2758659N,N-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)anilineYield 99%

Reagents, catalysts & solvents 5

HCID 6425PinacolReagentHCID 8471TriethylamineReagentHCID 67506CatecholboraneReagentHCID 582056Tris(pentafluorophenyl)boraneCatalystHCID 1140TolueneSolvent

Conditions

Temperature
120 °C

Sources & evidence

ORD record
ord-e432e9267a3c4917a54c918d2c72c6fd
Source dataset
Borylation dataset from Roche

Reaction notes

Loading…