1,1'-Biphenyl, 3-fluoro- (9CI) → HCID 17750246, compound

HRID 1490659Notes

Reaction equation

HRID 1490659 reaction equation
Fc1cccc(-c2ccccc2)c1>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.CC(C)(C)c1ccnc(-c2cc(C(C)(C)C)ccn2)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].[Ir].[Ir]>CC1(C)OB(c2ccc(-c3ccccc3)cc2F)OC1(C)C

Participants

6

Reactant 1

HCID 1456631,1'-Biphenyl, 3-fluoro- (9CI)

Product 1

HCID 17750246HCID 17750246, compoundYield 32%

Reagents, catalysts & solvents 4

HCID 2733548Bis(pinacolato)diboraneReagentHCID 42491874,4'-Di-tert-butyl-2,2'-bipyridylReagentHCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridiumCatalystHCID 8028TetrahydrofuranSolvent

Conditions

Temperature
50 °C

Sources & evidence

ORD record
ord-1ad22675475846fb998d75a7adb1d9b1
Source dataset
Borylation dataset from Roche

Reaction notes

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