Ethyl 2-(trifluoromethyl)benzoate → HCID 131389041, compound

HRID 1490721Notes

Reaction equation

HRID 1490721 reaction equation
CCOC(=O)c1ccccc1C(F)(F)F>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.CC(C)(C)O.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].O=c1ccc2cccc(-c3ccc(-c4ccccn4)nc3)c2[nH]1.[Ir].[Ir].[K]>CCOC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1C(F)(F)F

Participants

7

Reactant 1

HCID 521815Ethyl 2-(trifluoromethyl)benzoate

Product 1

HCID 131389041HCID 131389041, compoundYield 81%

Reagents, catalysts & solvents 5

HCID 2733548Bis(pinacolato)diboraneReagentHCID 86639980Potassium tert-butoxideReagentHCID 1646813858-([2,2'-bipyridin]-5-yl)quinolin-2(1H)-oneReagentHCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridiumCatalystHCID 8028TetrahydrofuranSolvent

Conditions

Temperature
50 °C

Sources & evidence

ORD record
ord-6d57b92e112f41258fec7416469fa927
Source dataset
Borylation dataset from Roche

Reaction notes

Loading…