Ethyl indole-5-carboxylate → HCID 178468680, compound

HRID 1490737Notes

Reaction equation

HRID 1490737 reaction equation
CCOC(=O)c1ccc2[nH]ccc2c1>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].O=c1ccc2cccc(-c3ccc(-c4ccccn4)nc3)c2[nH]1.[Ir].[Ir]>CCOC(=O)c1ccc2[nH]c(B3OC(C)(C)C(C)(C)O3)cc2c1

Participants

6

Reactant 1

HCID 10987040Ethyl indole-5-carboxylate

Product 1

HCID 178468680HCID 178468680, compoundYield 40%

Reagents, catalysts & solvents 4

HCID 2733548Bis(pinacolato)diboraneReagentHCID 1646813858-([2,2'-bipyridin]-5-yl)quinolin-2(1H)-oneReagentHCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridiumCatalystHCID 8028TetrahydrofuranSolvent

Conditions

Temperature
80 °C

Sources & evidence

ORD record
ord-6d453b12cc7944949967b9c6675621f0
Source dataset
Borylation dataset from Roche

Reaction notes

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