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HRID1490931

反应详情

EQUATION

反应方程式

HRID 1490931 的结构方程式

REACTANTS

反应物

1
结构：Cc1ccccc1C#N
HCID10721

2-Tolunitrile

C8H7N

PRODUCTS

生成物

2
结构：Cc1cc(B2OC(C)(C)C(C)(C)O2)ccc1C#N
HCID45158520

2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

C14H18BNO2

收率 52%
结构：Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1C#N
HCID53216769

2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

C14H18BNO2

收率 40%

AUXILIARIES

试剂、催化剂与溶剂

4
结构：CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C
试剂HCID2733548

Bis(pinacolato)diboron

C12H24B2O4

结构：CC(C)(C)c1ccnc(-c2cc(C(C)(C)C)ccn2)c1
试剂HCID4249187

未命名化合物

结构：C1=CCCC=CCC1.C1=CCCC=CCC1.C[OH2+].C[OH2+].[Ir].[Ir]
催化剂HCID76001521

未命名化合物

结构：COC(C)(C)C
溶剂HCID15413

Methyl tert-butyl ether

C5H12O

CONDITIONS

反应条件

温度
25 °C

PROCEDURE

实验过程

General procedure C was applied to 2-methylbenzonitrile 15g(47mg, 0.4mmol). The reaction mixture was stirredat room temperature for 16hours giving a conversion of >99% (GCMS) and 16g, 17gand 18in a 52:40:8 mixture (1H NMR spectrum).