1-(tert-Butoxycarbonyl)azetidine → 1-Azetidinecarboxylic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl ester

HRID 1491009Notes

Reaction equation

HRID 1491009 reaction equation
CC(C)(C)OC(=O)N1CCC1>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCCCCCC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].Cc1ccc2ccc3cccnc3c2n1.[Ir].[Ir]>CC(C)(C)OC(=O)N1CC(B2OC(C)(C)C(C)(C)O2)C1

Participants

6

Reactant 1

HCID 112059101-(tert-Butoxycarbonyl)azetidine

Product 1

HCID 1189920451-Azetidinecarboxylic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl esterYield 51%

Reagents, catalysts & solvents 4

HCID 2733548Bis(pinacolato)diboraneReagentHCID 49133562-Methyl-1,10-phenanthrolineReagentHCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridiumCatalystHCID 9266CyclooctaneSolvent

Conditions

Temperature
100 °C

Sources & evidence

ORD record
ord-823e3b40e1b94c91b06c91aacdefd398
Source dataset
Borylation dataset from Roche

Reaction notes

Loading…