HCID 669183, compound → HCID 178431057, compound

HRID 1491075Notes

Reaction equation

HRID 1491075 reaction equation
O=C(NCc1ccccc1)c1cccc(Cl)c1>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].Cc1[nH]c2c(NC(=O)c3ccc(-c4ccccn4)nc3)cccc2c1C.[Ir].[Ir]>CC1(C)OB(c2ccc(Cl)cc2C(=O)NCc2ccccc2)OC1(C)C

Participants

6

Reactant 1

HCID 669183HCID 669183, compound

Product 1

HCID 178431057HCID 178431057, compoundYield 39%

Reagents, catalysts & solvents 4

HCID 2733548Bis(pinacolato)diboraneReagentHCID 178433626HCID 178433626, compoundReagentHCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridiumCatalystHCID 8028TetrahydrofuranSolvent

Conditions

Temperature
60 °C

Procedure

Isolated by chromatography using deactivated silica gel and ethyl acetate and petroleum ether (10:0.5 to 10:4.0) as the eluent.

Sources & evidence

ORD record
ord-8d46bcf6b87847279ed547e98d08e82e
Source dataset
Borylation dataset from Roche

Reaction notes

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