HCID 65142863, compound → HCID 130053534, compound

HRID 1491238Notes

Reaction equation

HRID 1491238 reaction equation
Cc1cc(NC(=O)OC(C)(C)C)ccc1F>C1=CCCC=CCC1.C1=CCCC=CCC1.CC(C)(C)c1ccnc(-c2cc(C(C)(C)C)ccn2)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CC1(C)OBOC1(C)C.COC(C)(C)C.C[OH2+].C[OH2+].[Ir].[Ir]>Cc1cc(NC(=O)OC(C)(C)C)c(B2OC(C)(C)C(C)(C)O2)cc1F.Cc1cc(NC(=O)OC(C)(C)C)cc(B2OC(C)(C)C(C)(C)O2)c1F

Participants

8

Reactant 1

HCID 65142863HCID 65142863, compound

Product 2

HCID 130053534HCID 130053534, compoundYield 91%HCID 130058623HCID 130058623, compoundYield 9%

Reagents, catalysts & solvents 5

HCID 2733548Bis(pinacolato)diboraneReagentHCID 27347684,4,5,5-Tetramethyl[1,3,2]dioxaborolaneReagentHCID 42491874,4'-Di-tert-butyl-2,2'-bipyridylReagentHCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridiumCatalystHCID 15413tert-Butyl methyl etherSolvent

Conditions

Temperature
50 °C

Sources & evidence

ORD record
ord-4b80f86191694543b248d389a15efa05
Source dataset
Borylation dataset from Roche

Reaction notes

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