1,2,3-Trimethoxybenzene → 4,4,5,5-Tetramethyl-2-(3,4,5-trimethoxyphenyl)-1,3,2-dioxaborolane

HRID 1491311Notes

Reaction equation

HRID 1491311 reaction equation
COc1cccc(OC)c1OC>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.C1CCc2c(c3c(c4c2CCCC4)CCCC3)C1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].Cc1cnc2c(ccc3c(C)c(C)cnc32)c1C.[Ir].[Ir]>COc1cc(B2OC(C)(C)C(C)(C)O2)cc(OC)c1OC

Participants

7

Reactant 1

HCID 124621,2,3-Trimethoxybenzene

Product 1

HCID 219239464,4,5,5-Tetramethyl-2-(3,4,5-trimethoxyphenyl)-1,3,2-dioxaborolaneYield 93%

Reagents, catalysts & solvents 5

HCID 742653,4,7,8-Tetramethyl-1,10-phenanthrolineReagentHCID 95278DodecahydrotriphenyleneReagentHCID 2733548Bis(pinacolato)diboraneReagentHCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridiumCatalystHCID 8028TetrahydrofuranSolvent

Conditions

Temperature
80 °C

Sources & evidence

ORD record
ord-893de13e987b4151a777f1b065746492
Source dataset
Borylation dataset from Roche

Reaction notes

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