Potassium Carbonate → HCID 21459557, compound

HRID 1492057Notes

Reaction equation

HRID 1492057 reaction equation
[Br:1][C:2]1[C:6]([Br:7])=[C:5]([Br:8])[NH:4][C:3]=1[C:9]#[N:10].[C:11](=O)([O-])[O-].[K+].[K+].[I-].FC(F)(F)C1NC(Br)=C(Br)C=1C#N>CC(C)=O.C(COC)OC.O>[Br:1][C:2]1[C:6]([Br:7])=[C:5]([Br:8])[N:4]([CH3:11])[C:3]=1[C:9]#[N:10]

Participants

8

Reactant 4

HCID 11430Potassium CarbonateHCID 30165Iodide IonHCID 12040166HCID 12040166, compoundHCID 214595104,5-Dibromo-2-(trifluoromethyl)-1H-pyrrole-3-carbonitrile

Product 1

HCID 21459557HCID 21459557, compound

Reagents, catalysts & solvents 3

HCID 180AcetoneSolventHCID 962WaterSolventHCID 80711,2-DimethoxyethaneSolvent

Procedure

3,4,5-Tribromo-pyrrole-2-carbonitrile (1.0 g, 0.003 mo1) is dissolved in a mixture of acetone (20 mL) and dimethoxyethane (10 mL). Potassium carbonate (0.45 g, 0.0033 mol) is added followed by methyl .iodide (0.478 g, 0.0033 mo1). After stirring overnight at room temperature, the mixture is poured into water precipitating a white solid. The solid (0.S g, 80%) has mp 115°-119° C.

Sources & evidence

ORD record
ord-9a8dc11ce05f4874b84311ffd86ebcfa
Source dataset
uspto-grants-1994_12
Patent number
US05371239

Reaction notes

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