反应详情

To 20 g of N1 -cyano-N3 -(3,4-dichlorobenzyl)-guanidine and 13.5 g of 4-chloroaniline hydrochloride, 200 ml of water was added, which was heated and refluxed for 2 hours. When cooled gradually after reaction, crystals was precipiated. After filtering the crystals, by drying the crystals obtained by heat treatment in 200 ml of ethyl acetate, 21.8 g of the captioned compound was obtained.

1. temperaturewhich was heated
2. temperaturerefluxed for 2 hours
3. temperatureWhen cooled gradually
4. customafter reaction, crystals
5. filtrationAfter filtering the crystals
6. customby drying the crystals
7. customobtained