Methylamine → HCID 67893862, compound

HRID 1493236Notes

Reaction equation

HRID 1493236 reaction equation
[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[N:4][CH:3]=1.[CH3:9][NH2:10]>C1(C)C=CC=CC=1>[CH:1](=[CH:9][NH2:10])[C:2]1[CH:7]=[CH:6][CH:5]=[N:4][CH:3]=1

Participants

4

Reactant 2

HCID 6329MethylamineHCID 103713-Pyridinecarboxaldehyde

Product 1

HCID 67893862HCID 67893862, compoundYield 97.4%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Nicotinaldehyde (10.7 g, 0.1 mol) was dissolved in toluene (100 ml) and thereto was added 40% aqueous methylamine solution (23.3 g, 0.3 mol) and the mixture was subjected to azeotropic dehydration for 3 hours. The reaction mixture was concentrated under reduced pressure to obtain N-nicotinylidenemethylamine (11.7 g).

Workup

  1. concentrationThe reaction mixture was concentrated under reduced pressure

Sources & evidence

ORD record
ord-54eaf1083bea458f97058c1d4a496f6a
Source dataset
uspto-grants-1991_06
Patent number
US05021435

Reaction notes

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