3-Pyridinecarboxaldehyde → HCID 9989787, compound

HRID 1493238Notes

Reaction equation

HRID 1493238 reaction equation
[CH:1]1[CH:6]=[N:5][CH:4]=[C:3]([CH:7]=O)[CH:2]=1.[CH3:9][N:10]([CH3:14])[CH2:11][CH2:12][NH2:13]>C1(C)C=CC=CC=1>[CH:7](=[N:13][CH2:12][CH2:11][N:10]([CH3:14])[CH3:9])[C:3]1[CH:2]=[CH:1][CH:6]=[N:5][CH:4]=1

Participants

4

Reactant 2

HCID 103713-PyridinecarboxaldehydeHCID 66053N,N-Dimethylethylenediamine

Product 1

HCID 9989787HCID 9989787, compoundYield 102%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Nicotinealdehyde (2.16 ml, 22.9 mmol) and N,N-dimethylethylenediamine (2.51 ml, 22.9 mmol) were added to toluene (100 ml) and the mixture was subjected to azeotropic dehydration for 2 hours. After cooling, solvent was distilled off to obtain N-nicotinylidene-N',N'-dimethylethylenediamine (4.13 g, yield 102%).

Workup

  1. temperatureAfter cooling
  2. distillationsolvent was distilled off

Sources & evidence

ORD record
ord-03ac82eee3b44876bb2f0cce64a26396
Source dataset
uspto-grants-1991_06
Patent number
US05021435

Reaction notes

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