Methane → HCID 19108679, compound

HRID 1493992Notes

Reaction equation

HRID 1493992 reaction equation
[S:1](Cl)(=[O:4])(=[O:3])[NH2:2].[Cl:6][C:7]1[CH:8]=[C:9]([CH:14]=[CH:15][C:16]=1[Cl:17])[O:10][CH2:11][CH2:12][OH:13].C>C(OC(C)C)(C)C>[Cl:6][C:7]1[CH:8]=[C:9]([CH:14]=[CH:15][C:16]=1[Cl:17])[O:10][CH2:11][CH2:12][O:13][S:1](=[O:4])(=[O:3])[NH2:2]

Participants

5

Reactant 3

HCID 297MethaneHCID 24499Chlorosulfamic acidHCID 191086922-(3,4-Dichlorophenoxy)ethanol

Product 1

HCID 19108679HCID 19108679, compound

Reagents, catalysts & solvents 1

HCID 7914Diisopropyl EtherSolvent

Procedure

The title compound was prepared by the procedures of Example 16 from sulfamoyl chloride and to 2-(3,4-dichlorophenoxy)ethanol. The tan colored solid obtained was dissolved in isopropyl ether and the solution treated with charcoal and filtered through Celite®. The filtrate was evaporated under reduced pressure and the solid residue was recrystallized from isopropyl ether to give the title compound, mp 84°-85° C., in 19% yield.

Workup

  1. customThe tan colored solid obtained
  2. filtrationfiltered through Celite®
  3. customThe filtrate was evaporated under reduced pressure
  4. customthe solid residue was recrystallized from isopropyl ether

Sources & evidence

ORD record
ord-05faf73ec11741949f749a017da5168e
Source dataset
uspto-grants-1991_06
Patent number
US05025031

Reaction notes

Loading…