Hydrochloric Acid → HCID 13715242, compound

HRID 1494315Notes

Reaction equation

HRID 1494315 reaction equation
Cl.[CH3:2][CH:3]1[C:8]([C:9]2[CH:14]=[CH:13][C:12]([NH:15][C:16](=[O:23])[C:17]3[CH:22]=[CH:21][CH:20]=[N:19][CH:18]=3)=[C:11]([NH2:24])[CH:10]=2)=[N:7][NH:6][C:5](=[O:25])[CH2:4]1>C(O)(C)C>[OH2:23].[OH2:23].[CH3:2][CH:3]1[C:8]([C:9]2[CH:14]=[CH:13][C:12]3[N:15]=[C:16]([C:17]4[CH:18]=[N:19][CH:20]=[CH:21][CH:22]=4)[NH:24][C:11]=3[CH:10]=2)=[N:7][NH:6][C:5](=[O:25])[CH2:4]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19827883HCID 19827883, compound

Product 1

HCID 13715242HCID 13715242, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

HCl gas is passed for 2 hours into a boiling suspension of 1 g of 5-methyl-6-(3-amino-4-nicotinamidophenyl)-4,5-dihydropyridazin-3-one in 50 ml of isopropanol. After evaporation and the usual working up, 5-methyl-6-[2-(3-pyridyl)-5-benzimidazolyl]-4,5-dihydropyridazin-3-one, dihydrate, decomposition above 173°, is obtained.

Workup

  1. customAfter evaporation

Sources & evidence

ORD record
ord-f45124a49dd64737a376c807326ca94f
Source dataset
uspto-grants-1991_06
Patent number
US05026705

Reaction notes

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