Sodium Hydroxide → HCID 19828691, compound

HRID 1494579Notes

Reaction equation

HRID 1494579 reaction equation
[SH:1][C:2]1[S:3][C:4]([SH:7])=[N:5][N:6]=1.[CH2:8]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[CH:9]1[O:11][CH2:10]1.[OH-].[Na+].[CH2:27]([O:31][CH2:32][CH2:33][CH2:34][CH3:35])[CH:28]1[O:30][CH2:29]1>C(O)(C)C>[CH2:13]([O:12][CH2:8][CH:9]([OH:11])[CH2:10][S:1][C:2]1[S:3][C:4]([S:7][CH2:29][CH:28]([OH:30])[CH2:27][O:31][CH2:32][CH2:33][CH2:34][CH3:35])=[N:5][N:6]=1)[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]

Participants

6

Reactant 4

HCID 14798Sodium HydroxideHCID 17049Butyl glycidyl etherHCID 171631-Dodecyl glycidyl etherHCID 178418558HCID 178418558, compound

Product 1

HCID 19828691HCID 19828691, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

2,5-Dimercapto-1,3,4-thiadiazole(51.64 grams, 0.34 moles) and isopropanol(150 ml) were added to the reaction flask. Dodecyl glycidyl ether(87.35 grams, 0.34 moles) was slowly added with cooling to maintain the temperature below 25° C. Then sodium hydroxide(0.05 grams) was added followed by butyl glycidyl ether (44.91 grams, 0.34 moles). The reaction mixture was refluxed for 15 minutes and the solvent was stripped off by using a rotary evaporator. The product was characterized by infrared absorption bands at 3200, 2900, 1460, 1385, 1260, 1120, 1050, and 710 cm-1.

Workup

  1. temperaturewith cooling
  2. temperatureto maintain the temperature below 25° C
  3. temperatureThe reaction mixture was refluxed for 15 minutes
  4. customa rotary evaporator
  5. customThe product was characterized by infrared absorption bands at 3200, 2900, 1460, 1385, 1260, 1120, 1050, and 710 cm-1

Sources & evidence

ORD record
ord-377d95f6bc654a319bd7190e4ec1aeaa
Source dataset
uspto-grants-1991_06
Patent number
US05026865

Reaction notes

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