Tert-Butylamine → HCID 14851222, compound

HRID 1494676Notes

Reaction equation

[OH:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[N+:11]([O-:13])=[O:12])[C:5]([OH:7])=[O:6].[Br:14]Br.[C:16](N)([CH3:19])(C)C>>[Br:14][C:3]1[C:2]([OH:1])=[C:10]([N+:11]([O-:13])=[O:12])[CH:9]=[CH:8][C:4]=1[C:5]([O:7][CH2:16][CH3:19])=[O:6]

Participants

Reactant 3

HCID 6385Tert-Butylamine

HCID 24408Bromine

HCID 692653-Hydroxy-4-nitrobenzoic acid

Product 1

HCID 14851222HCID 14851222, compoundYield 70.1%

Procedure

A 0.1 mole of the ethyl ester of 3-hydroxy-4-nitrobenzoic acid was monobrominated using the procedure described in Example 1, except only one equivalent of bromine and two equivalents of t-butyl amine were used. This reaction yielded ethyl 2-bromo-3-hydroxy-4-nitrobenzoate in 70.1% yield. It had a melting point of 58°-61° C.

Sources & evidence

ORD record: ord-f1999c3815574bde871143fa1f1b8bb8
Source dataset: uspto-grants-1991_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05026896

Reaction notes

Loading…