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HRID1494733

反应详情

EQUATION

反应方程式

HRID 1494733 的结构方程式

REACTANTS

反应物

3
结构：C1CCC2=NCCCN2CC1
HCID81184

1,8-Diazabicyclo[5.4.0]undec-7-ene

C9H16N2

结构：CC1COc2c(F)c(F)cc3c(=O)c(C(=O)O)cn1c23
HCID534278

未命名化合物

结构：CCNc1ccc2c(c1)CNC2
HCID14795863

N-Ethyl-2,3-dihydro-1H-isoindol-5-amine

C10H14N2

PRODUCTS

生成物

1
结构：CCNc1ccc2c(c1)CN(c1c(F)cc3c(=O)c(C(=O)O)cn4c3c1OCC4C)C2
HCID15167917

未命名化合物

收率 51.3%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

141 mg of 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido [1,2,3-de][1,4]-benzoxazine-6-carboxylic acid, 97 mg of 5-ethylaminoisoindoline, 152 mg of DBU, and 1.5 ml of anhydrous DMF were processed in the same manner as in Example 1 to produce 109 mg of the target compound.