HRID1494739

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID81184

1,8-Diazabicyclo[5.4.0]undec-7-ene

C9H16N2

HCID5210422

1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

C13H9F2NO3

HCID14795861

2,3-Dihydro-1H-isoindol-4-amine

C8H10N2

PRODUCTS

生成物

结构：Nc1cccc2c1CN(c1cc3c(cc1F)c(=O)c(C(=O)O)cn3C1CC1)C2

HCID14795761

未命名化合物

收率 51%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

133 mg of 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 81 mg of 4-aminoisoindoline, 182 mg of DBU, and 1.5 ml of anhydrous DMF were processed in the same manner as in Example 2 to produce 97 mg of the target compound.