HRID1494744

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C(O)c1cn(C2CC2)c2c(F)c(F)c(F)cc2c1=O

HCID535414

1-CYCLOPROPYL-6,7,8-TRIFLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID

C13H8F3NO3

HCID14795867

4-Fluoro-2,3-dihydro-1H-isoindole

C8H8FN

PRODUCTS

生成物

结构：O=C(O)c1cn(C2CC2)c2c(F)c(N3Cc4cccc(F)c4C3)c(F)cc2c1=O

HCID14795766

未命名化合物

收率 66.1%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

136 mg of 1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4- oxoquinoline-3-carboxylic acid, 206 mg of 4-fluoroisoindoline, and 1.5 ml of anhydrous DMF were processed in the same manner as in Example 20 to produce 127 mg of the target compound.