huagongshe.com
HRID1494746

反应详情

EQUATION

反应方程式

HRID 1494746 的结构方程式

REACTANTS

反应物

3
结构：C1CCC2=NCCCN2CC1
HCID81184

1,8-Diazabicyclo[5.4.0]undec-7-ene

C9H16N2

结构：CC1COc2c(F)c(F)cc3c(=O)c(C(=O)O)cn1c23
HCID534278

未命名化合物

结构：Clc1cccc2c1CNC2
HCID14795868

4-Chloro-2,3-dihydro-1H-isoindole

C8H8ClN

PRODUCTS

生成物

1
结构：CC1COc2c(N3Cc4cccc(Cl)c4C3)c(F)cc3c(=O)c(C(=O)O)cn1c23
HCID15167920

未命名化合物

收率 33.7%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

141 mg of 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]-benzoxazine-6-carboxylic acid, 115 mg of 4-chloroisoindoline, 114 mg of DBU, and 1.5 ml of anhydrous DMF were processed in the same manner as in Example 20 to produce 70 mg of the target compound.