HRID1494771

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID81184

1,8-Diazabicyclo[5.4.0]undec-7-ene

C9H16N2

HCID14795864

4-Methoxy-2,3-dihydro-1H-isoindole

C9H11NO

结构：O=C(O)c1cn(C2CC2)c2c(F)c(F)c(F)c(NCCO)c2c1=O

HCID19828486

未命名化合物

PRODUCTS

生成物

结构：COc1cccc2c1CN(c1c(F)c(NCCO)c3c(=O)c(C(=O)O)cn(C4CC4)c3c1F)C2

HCID14795788

未命名化合物

收率 46.4%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

205 mg of 1-cyclopropyl-5-(2-hydroxyethylamino)-6,7,8- trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 150 mg of 4-methoxyisoindoline, 182 mg of DBU, and 1.5 ml of anhydrous DMF were processed in the same manner as in Example 20 to produce 131 mg of the target compound.