HRID1494774

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID81184

1,8-Diazabicyclo[5.4.0]undec-7-ene

C9H16N2

HCID14795870

4-Bromo-2,3-dihydro-1H-isoindole

C8H8BrN

结构：O=C(O)c1cn(C2CC2)c2c(F)c(F)c(F)c(NCCO)c2c1=O

HCID19828486

未命名化合物

PRODUCTS

生成物

结构：O=C(O)c1cn(C2CC2)c2c(F)c(N3Cc4cccc(Br)c4C3)c(F)c(NCCO)c2c1=O

HCID14795792

未命名化合物

收率 32.7%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

205 mg of 1-cyclopropyl-5-(2-hydroxyethylamino)-6,7,8- trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 131 mg of 4-bromoisoindoline, 182 mg of DBU, and 1.5 ml of are anhydrous DMF were processed in the same manner as in Example 20 to produce 102 mg of the target compound.