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HRID1494779

反应详情

EQUATION

反应方程式

HRID 1494779 的结构方程式

REACTANTS

反应物

3
结构：C1CCC2=NCCCN2CC1
HCID81184

1,8-Diazabicyclo[5.4.0]undec-7-ene

C9H16N2

结构：O=C(O)c1cn(C2CC2)c2cc(F)c(F)cc2c1=O
HCID5210422

1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

C13H9F2NO3

结构：Br.O=[N+]([O-])c1cccc2c1CNC2
HCID19828497

未命名化合物

PRODUCTS

生成物

1
结构：O=C(O)c1cn(C2CC2)c2cc(N3Cc4cccc([N+](=O)[O-])c4C3)c(F)cc2c1=O
HCID14795794

未命名化合物

收率 33.4%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

159 mg of 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 176 mg of 4-nitroisoindoline hydrobromide, 164 mg of DBU, and 1.5 ml of anhydrous DMF were processed in the same manner as in Example 20 to produce 82 mg of the target compound.