huagongshe.com
HRID1494808

反应详情

EQUATION

反应方程式

HRID 1494808 的结构方程式

REACTANTS

反应物

3
结构：C1CCC2=NCCCN2CC1
HCID81184

1,8-Diazabicyclo[5.4.0]undec-7-ene

C9H16N2

结构：O=C(O)c1cn(C2CC2)c2c(F)c(F)c(F)cc2c1=O
HCID535414

1-CYCLOPROPYL-6,7,8-TRIFLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID

C13H8F3NO3

结构：OCc1cccc2c1CNC2
HCID19828510

(2,3-Dihydro-1H-isoindol-4-yl)methanol

C9H11NO

PRODUCTS

生成物

1
结构：O=C(O)c1cn(C2CC2)c2c(F)c(N3Cc4cccc(CO)c4C3)c(F)cc2c1=O
HCID14795800

未命名化合物

收率 41.3%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

283 mg of 1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 179 mg of 4-hydroxymethylisoindoline, 304 mg of DBU, and 2 ml of anhydrous DMF were processed in the same manner as in Example 20 to produce 170 mg of the target compound.