HRID1494809

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID81184

1,8-Diazabicyclo[5.4.0]undec-7-ene

C9H16N2

结构：CC1COc2c(F)c(F)cc3c(=O)c(C(=O)O)cn1c23

HCID534278

未命名化合物

HCID19828510

(2,3-Dihydro-1H-isoindol-4-yl)methanol

C9H11NO

PRODUCTS

生成物

结构：CC1COc2c(N3Cc4cccc(CO)c4C3)c(F)cc3c(=O)c(C(=O)O)cn1c23

HCID15167927

未命名化合物

收率 29.3%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

281 mg of 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido [1,2,3-de][1,4]-benzoxazine-6-carboxylic acid, 179 mg of 4-hydroxymethylisoindoline, 304 mg of DBU, and 2 ml of anhydrous DMF were processed in the same manner as in Example 20 to produce 120 mg of the target compound.