Dichloromethane → HCID 60043780, compound

HRID 149501Notes

Reaction equation

HRID 149501 reaction equation
[C:41]([c:42]1[nH:43][cH:44][cH:45][n:46]1)(=[O:47])[CH3:48].[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[Cl:56][CH2:57][Cl:58].[Cl:59][CH2:60][Cl:61].[F:1][c:2]1[cH:3][c:4]([CH2:5][CH:6]([CH:7]([CH2:8][NH:9][CH:10]2[CH2:11][CH2:12][O:13][c:14]3[cH:15][cH:16][c:17]([I:20])[cH:18][c:19]32)[OH:21])[NH:22][C:23]([O:24][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:25])[cH:30][c:31]([F:33])[cH:32]1.[F:49][C:50]([F:51])([F:52])[C:53]([OH:54])=[O:55]>>[F:1][c:2]1[cH:3][c:4]([CH2:5][CH:6]([CH:7]([CH2:8][NH:9][CH:10]2[CH2:11][CH2:12][O:13][c:14]3[cH:15][cH:16][c:17]([I:20])[cH:18][c:19]32)[OH:21])[NH:22][C:23](=[O:24])[CH3:34])[cH:30][c:31]([F:33])[cH:32]1

Participants

6

Reactant 5

HCID 6344Dichloromethane2×HCID 6422Trifluoroacetic acidHCID 8471TriethylamineHCID 5389722-AcetylimidazoleHCID 60043785tert-butyl N-[1-(3,5-difluorophenyl)-3-hydroxy-4-[(6-iodo-3,4-dihydro-2H-chromen-4-yl)amino]butan-2-yl]carbamate

Product 1

HCID 60043780HCID 60043780, compound

Sources & evidence

ORD record
ord-e622d68e7dc84f098b3455bc29acb2ec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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