Ethanol → 7-[1-(3-Formylpyridin-4-yl)piperidin-4-ylmethoxy]-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([O:18][CH2:19][CH:20]3[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]3)[cH:13][cH:14][c:15]2[CH2:16][CH2:17]1.[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[CH3:47][CH2:48][OH:49].[CH3:50][CH2:51][O:52][CH2:53][CH3:54].[Cl:33][c:34]1[c:35]([CH:40]=[O:41])[cH:36][n:37][cH:38][cH:39]1.[O:42]1[CH2:43][CH2:44][CH2:45][CH2:46]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([O:18][CH2:19][CH:20]3[CH2:21][CH2:22][N:23]([c:34]4[c:35]([CH:40]=[O:41])[cH:36][n:37][cH:38][cH:39]4)[CH2:24][CH2:25]3)[cH:13][cH:14][c:15]2[CH2:16][CH2:17]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-f36842ca43294e07b8cd2c408cb8fe02
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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