Water → 5-(2-Chloro-5-fluoropyrimidin-4-yl)-N-methyl-N-phenylthiazol-2-amine
Reaction equation
[C:1]([Li:2])([CH3:3])([CH3:4])[CH3:5].[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:13][N:14]([c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)[c:21]1[s:22][cH:23][cH:24][n:25]1.[CH3:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[Cl:26][c:27]1[n:28][cH:29][c:30]([F:33])[cH:31][n:32]1.[Cl:34][C:35]1=[C:46]([Cl:47])[C:44](=[O:45])[C:41]([C:42]#[N:43])=[C:38]([C:39]#[N:40])[C:36]1=[O:37].[OH2:53]>>[CH3:13][N:14]([c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)[c:21]1[s:22][c:23](-[c:31]2[c:30]([F:33])[cH:29][n:28][c:27]([Cl:26])[n:32]2)[cH:24][n:25]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-018ee25a6e064661a621fb5e8e13153f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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