Hydrochloric Acid → Dimethyl 2-(3,4-difluorophenyl)piperidine-1,4-dicarboxylate
Reaction equation
[CH:20]([N:21]([CH2:22][CH3:23])[CH:24]([CH3:25])[CH3:26])([CH3:27])[CH3:28].[Cl:29][C:30](=[O:31])[O:32][CH3:33].[Cl:34][CH2:35][Cl:36].[ClH:1].[F:2][c:3]1[cH:4][c:5]([CH:10]2[NH:11][CH2:12][CH2:13][CH:14]([C:16](=[O:17])[O:18][CH3:19])[CH2:15]2)[cH:6][cH:7][c:8]1[F:9]>>[F:2][c:3]1[cH:4][c:5]([CH:10]2[N:11]([C:30](=[O:31])[O:32][CH3:33])[CH2:12][CH2:13][CH:14]([C:16](=[O:17])[O:18][CH3:19])[CH2:15]2)[cH:6][cH:7][c:8]1[F:9]Participants
6
Sources & evidence
- ORD record
- ord-da3d2a6b557f4b8ebd48e3cc10553be8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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