Isobutyryl chloride → 2-Isobutyryl-1-methylhydrazinecarboxamide

HRID 1498059Notes

Reaction equation

HRID 1498059 reaction equation
[CH3:1][N:2]([C:4]([NH2:6])=[O:5])[NH2:3].[C:7](Cl)(=[O:11])[CH:8]([CH3:10])[CH3:9]>C(N(CC)CC)C.ClCCl>[C:7]([NH:3][N:2]([CH3:1])[C:4]([NH2:6])=[O:5])(=[O:11])[CH:8]([CH3:10])[CH3:9]

Participants

5

Reactant 2

HCID 62325Isobutyryl chlorideHCID 2560041-Amino-1-methylurea

Product 1

HCID 582047742-Isobutyryl-1-methylhydrazinecarboxamide

Reagents, catalysts & solvents 2

HCID 6344DichloromethaneSolventHCID 8471TriethylamineSolvent

Procedure

1-Methylhydrazinecarboxamide was acylated with isobutyryl chloride in triethylamine and dichloromethane to give 2-isobutyryl-1-methylhydrazinecarboxamide.

Sources & evidence

ORD record
ord-8f7d003afb454ab783b2ca3316a370f4
Source dataset
uspto-grants-2015_12
Patent number
US09198918B2

Reaction notes

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