Butanal → HCID 86714715, compound

HRID 1500134Notes

Reaction equation

C(=O)([O-])[O-].[K+].[K+].[CH2:7]([NH:11][CH2:12][CH:13]([CH3:15])[CH3:14])[CH:8]([CH3:10])[CH3:9].[CH:16](=O)[CH2:17][CH2:18][CH3:19]>>[CH:16](/[N:11]([CH2:12][CH:13]([CH3:15])[CH3:14])[CH2:7][CH:8]([CH3:10])[CH3:9])=[CH:17]\[CH2:18][CH3:19]

Participants

Reactant 3

HCID 261Butanal

HCID 8085Diisobutylamine

HCID 11430Potassium Carbonate

Product 1

HCID 86714715HCID 86714715, compoundYield 74.2%

Conditions

Temperature: -7 °C

Procedure

Potassium carbonate (4.8 g, 35 mmol) was added to diisobutylamine (17.5 mL, 0.10 mol) under a nitrogen atmosphere, and the mixture was then cooled to −7° C. Butanal (9.0 mL, 0.10 mol) was added dropwise thereto over 10 minutes. The reaction mixture was gradually heated to room temperature and stirred for 19 hours. Insoluble matter was filtered off, and the filtrate was then concentrated under reduced pressure to obtain the title compound (13.6 g, yield: 74%) as a colorless oil substance.

Workup

temperatureThe reaction mixture was gradually heated to room temperature
filtrationInsoluble matter was filtered off
concentrationthe filtrate was then concentrated under reduced pressure

Sources & evidence

ORD record: ord-d3ed4f51ff6f4a69b66cca31fff6794f
Source dataset: uspto-grants-2015_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09206104B2

Reaction notes

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