Propanal → HCID 45277204, compound

HRID 1500160Notes

Reaction equation

HRID 1500160 reaction equation
[CH:1](=[O:4])[CH2:2][CH3:3].[N+:5](/[CH:8]=[CH:9]/[C:10]1[O:11][CH:12]=[CH:13][CH:14]=1)([O-:7])=[O:6].CC(O)C.CCCCCC>C(Cl)(Cl)Cl>[O:11]1[CH:12]=[CH:13][CH:14]=[C:10]1[C@H:9]([CH2:8][N+:5]([O-:7])=[O:6])[C@H:2]([CH3:3])[CH:1]=[O:4]

Participants

6

Reactant 4

HCID 527PropanalHCID 3776IsopropanolHCID 8058HexaneHCID 6873312-(B-NITROVINYL)FURAN

Product 1

HCID 45277204HCID 45277204, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The title compound was prepared from propionaldehyde and (E)-2-(2-nitro-vinyl)furan according to the general procedure. Both enantiomeric excess and diastereomeric ratio were determined by HPLC with an AD-H column at 220 nm (2-propanol:hexane=0.8:99.2), 1.0 mL/min; major enantiomer tmajor=30.44 min, minor enantiomer tminor=26.29 min. [α]D20=−20 (c=2.0, CHCl3).

Workup

  1. customtmajor=30.44 min, minor enantiomer

Sources & evidence

ORD record
ord-496233dd46b64a41948cc26a22e0b2b9
Source dataset
uspto-grants-2015_12
Patent number
US09206090B2

Reaction notes

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