Isopropanol → HCID 53230401, compound

HRID 1500164Notes

Reaction equation

HRID 1500164 reaction equation
[N+:1](/[CH:4]=[CH:5]/[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)([O-:3])=[O:2].[CH:12](=[O:16])[CH:13]([CH3:15])[CH3:14].CC(O)C.CCCCCC>C(Cl)(Cl)Cl>[CH3:14][C:13]([CH3:15])([C@H:5]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[CH2:4][N+:1]([O-:3])=[O:2])[CH:12]=[O:16]

Participants

6

Reactant 4

HCID 3776IsopropanolHCID 6561IsobutyraldehydeHCID 8058HexaneHCID 5284459beta-nitrostyrene, (E)-

Product 1

HCID 53230401HCID 53230401, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The title compound was prepared from (E)-(2-nitrovinyl)benzene and isobutyraldehyde according to the general procedure. The enantiomeric ratio were determined by HPLC with Chiralpak OD-H column at 210 nm (2-propanol:hexane=15:85), 1 mL/min, tmajor=19.7 min, tminor=13.9 min, [α]D20=−4.3 (c=1.6, CHCl3).

Sources & evidence

ORD record
ord-86f6eebd2b084a3e8aa5f7b8c92f4a40
Source dataset
uspto-grants-2015_12
Patent number
US09206090B2

Reaction notes

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