Isopropanol → HCID 58500175, compound

HRID 1500168Notes

Reaction equation

HRID 1500168 reaction equation
[N+:1](/[CH:4]=[CH:5]/[C:6]1[CH:15]=[CH:14][C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=1)([O-:3])=[O:2].[CH:16](=[O:20])[CH:17]([CH3:19])[CH3:18].CC(O)C.CCCCCC>C(Cl)(Cl)Cl>[CH3:18][C:17]([CH3:19])([C@H:5]([C:6]1[CH:15]=[CH:14][C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=1)[CH2:4][N+:1]([O-:3])=[O:2])[CH:16]=[O:20]

Participants

6

Reactant 4

HCID 3776IsopropanolHCID 6561IsobutyraldehydeHCID 8058HexaneHCID 53579632-(2-Nitrovinyl)naphthalene

Product 1

HCID 58500175HCID 58500175, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The title compound was prepared from (E)-2-(2-nitrovinyl)naphthalene and isobutyraldehyde according to General Procedure. The enantiomeric excess was determined by HPLC with Chiralpak AS-H column at 210 nm (2-propanol:hexane=10:90), 1 mL/min, tmajor=16.2 min, tminor=18.0 min, [α]D20=+1.7 (c=1.8, CHCl3)

Sources & evidence

ORD record
ord-db8e038d021249698c494c34747938b6
Source dataset
uspto-grants-2015_12
Patent number
US09206090B2

Reaction notes

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