Isopropanol → HCID 58500186, compound

HRID 1500171Notes

Reaction equation

HRID 1500171 reaction equation
[N+:1](/[CH:4]=[CH:5]/[C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:9]=[CH:8][CH:7]=1)([O-:3])=[O:2].[CH:16](=[O:21])[CH2:17][CH:18]([CH3:20])[CH3:19].CC(O)C>CCCCCC>[CH:18]([C@@H:17]([C@H:5]([C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:9]=[CH:8][CH:7]=1)[CH2:4][N+:1]([O-:3])=[O:2])[CH:16]=[O:21])([CH3:20])[CH3:19]

Participants

5

Reactant 3

HCID 3776IsopropanolHCID 115523-MethylbutanalHCID 538167937630-26-5

Product 1

HCID 58500186HCID 58500186, compound

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

The title compound was prepared from (E)-1-(2-nitrovinyl)naphthalene and isovaleraldehyde according to general procedure. The enantiomeric excess was determined by HPLC with Chiralpak AD-H column at 254 nm (2-propanol:hexane=10:90), 1 mL/min, tmajor=13.7 min, tminor 16.8 min, the diastereomeric ratio was determined by

Sources & evidence

ORD record
ord-e96e64b1b10f4758aa61d7efa365fb13
Source dataset
uspto-grants-2015_12
Patent number
US09206090B2

Reaction notes

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