Carbon Tetrachloride → Ethyl 2-chloro-2-(o-tolylimino)acetate

HRID 1506628Notes

Reaction equation

HRID 1506628 reaction equation
O=[C:2]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH3:15])[C:3]([O:5][CH2:6][CH3:7])=[O:4].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C(Cl)(Cl)(Cl)[Cl:36]>>[Cl:36][C:2](=[N:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH3:15])[C:3]([O:5][CH2:6][CH3:7])=[O:4]

Participants

4

Reactant 3

HCID 5943Carbon TetrachlorideHCID 11776TriphenylphosphineHCID 366755Ethyl [(2-methylphenyl)amino](oxo)acetate

Product 1

HCID 90280270Ethyl 2-chloro-2-(o-tolylimino)acetate

Procedure

The suspension of ethyl 2-oxo-2-(o-tolylamino)acetate (2.0 g, 10 mmol) and triphenylphosphine (4.0 g, 15 mmol) in carbon tetrachloride (150 mL) was refluxed overnight. The reaction was cooled down and filtered. The filtrate was collected and concentrated and used it without further purification. MS (m/z) 226 [M+H]+.

Workup

  1. temperaturewas refluxed overnight
  2. temperatureThe reaction was cooled down
  3. filtrationfiltered
  4. customThe filtrate was collected
  5. concentrationconcentrated
  6. customwithout further purification

Sources & evidence

ORD record
ord-e2541b6eee964802a631689e192c3bde
Source dataset
uspto-grants-2015_12
Patent number
US09220710B2

Reaction notes

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