7-Chloro-2-mercaptobenzothiazole → 7-Chloro-1,3-benzothiazole

HRID 1507523Notes

Reaction equation

HRID 1507523 reaction equation
[Cl:1][C:2]1[C:10]2[S:9][C:8](S)=[N:7][C:6]=2[CH:5]=[CH:4][CH:3]=1>C(O)(=O)C.[Fe]>[Cl:1][C:2]1[C:10]2[S:9][CH:8]=[N:7][C:6]=2[CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 1

HCID 1785277847-Chloro-2-mercaptobenzothiazole

Product 1

HCID 184112937-Chloro-1,3-benzothiazole

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 176Acetic AcidSolvent

Procedure

Following the same procedure in step 2 of Example 337 using 7-chloro-1,3-benzothiazole-2-thiol (700 mg, 3.47 mmol, 1.00 equiv) and iron powder (1.94 g, 10.00 equiv) in acetic acid (20.0 mL) (gray white solid).

Sources & evidence

ORD record
ord-0ff600dd649f4fccbf17228fe6539ee7
Source dataset
uspto-grants-2015_12
Patent number
US09221809B2

Reaction notes

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