反应详情

To a solution of furo[2,3-c]pyridin-3(2H)-one O-methyl oxime (5.35 mmol) (A.2.4.4) in 15 mL DCM was added 3-chloroperbenzoic acid (16.0 mmol). The mixture was stirred at RT overnight, diluted with 20 mL DCM and extracted with sat. aq. NaHCO3 solution (2×), with sat. aq. Na2S2O3 solution (2×) and brine. The combined organic layers were dried over MgSO4 and concentrated in vacuo to give the desired product as yellow solid;

1. extractionextracted with sat. aq. NaHCO3 solution (2×), with sat. aq. Na2S2O3 solution (2×) and brine
2. dry with materialThe combined organic layers were dried over MgSO4
3. concentrationconcentrated in vacuo