Potassium Carbonate → HCID 25126267, compound

HRID 1509797Notes

Reaction equation

HRID 1509797 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1.[N+:8]([C:11]1[CH:16]=[CH:15][C:14](F)=[CH:13][C:12]=1[C:18]1[O:19][C:20]2[CH:26]=[CH:25][CH:24]=[CH:23][C:21]=2[N:22]=1)([O-:10])=[O:9].C([O-])([O-])=O.[K+].[K+]>CS(C)=O>[N+:8]([C:11]1[CH:16]=[CH:15][C:14]([CH:3]2[CH2:4][NH:5][CH2:6][CH2:7][N:2]2[CH3:1])=[CH:13][C:12]=1[C:18]1[O:19][C:20]2[CH:26]=[CH:25][CH:24]=[CH:23][C:21]=2[N:22]=1)([O-:10])=[O:9]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 531671-MethylpiperazineHCID 25125945HCID 25125945, compound

Product 1

HCID 25126267HCID 25126267, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Conditions

Temperature
90 °C

Procedure

1.01 g (0.010 mol) of N-methylpiperazine were added to the mixture of 1.29 g (0.005 mol) of 2-(2′-nitro-5′-fluorophenyl)benzoxazole and 1.04 g (0.0075 mol) of K2CO3 in 9 ml of dimethyl sulfoxide. The reaction was stirred magnetically and heated at 90° C., the progression thereof being verified by TLC.

Sources & evidence

ORD record
ord-3cc9fabc0ba3417791213a7d24db1223
Source dataset
uspto-grants-2012_07
Patent number
US08211662B2

Reaction notes

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