3,4-Diaminotoluene → HCID 59590552, compound

HRID 1509993Notes

Reaction equation

HRID 1509993 reaction equation
[C:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=O)=[CH:5][CH:4]=1)#[N:2].[CH3:12][C:13]1[CH:18]=[CH:17][C:16]([NH2:19])=[C:15]([NH2:20])[CH:14]=1>>[NH2:2][CH2:1][C:3]1[CH:4]=[CH:5][C:6]([C:7]([NH:19][C:16]2[CH:17]=[CH:18][C:13]([CH3:12])=[CH:14][C:15]=2[NH2:20])=[O:9])=[CH:10][CH:11]=1

Participants

3

Reactant 2

HCID 103323,4-DiaminotolueneHCID 120874-Cyanobenzoic acid

Product 1

HCID 59590552HCID 59590552, compoundYield 68%

Procedure

The title compound (173 mg, 68% yield) was prepared as a grey solid from 4-cyano-benzoic acid (294 mg, 2 mmol) and 4-methyl-o-phenylenediamine (293 mg, 2.4 mmol) by an analogous procedure to that described in example 8. LC-MS (m/z) 256 (M+1).

Sources & evidence

ORD record
ord-bb2ae5682d2f4dda99ffe532ebf58a96
Source dataset
uspto-grants-2012_07
Patent number
US08211901B2

Reaction notes

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