4-Cyanobenzoic acid → HCID 59590550, compound

HRID 1509994Notes

Reaction equation

HRID 1509994 reaction equation
[C:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=O)=[CH:5][CH:4]=1)#[N:2].[CH3:12][O:13][C:14]1[CH:19]=[CH:18][C:17]([NH2:20])=[C:16]([NH2:21])[CH:15]=1>>[NH2:2][CH2:1][C:3]1[CH:4]=[CH:5][C:6]([C:7]([NH:20][C:17]2[CH:18]=[CH:19][C:14]([O:13][CH3:12])=[CH:15][C:16]=2[NH2:21])=[O:9])=[CH:10][CH:11]=1

Participants

3

Reactant 2

HCID 120874-Cyanobenzoic acidHCID 1534044-Methoxy-o-phenylenediamine

Product 1

HCID 59590550HCID 59590550, compoundYield 71%

Procedure

The title compound (192 mg, 71% yield) was prepared as a grey solid from 4-cyano-benzoic acid (294 mg, 2 mmol) and 4-methoxy-o-phenylenediamine (331 mg, 2.4 mmol) by an analogous procedure to that described in example 8. LC-MS (m/z) 272 (M+1).

Sources & evidence

ORD record
ord-338907a25b2f4502b23d4992fd83b3f7
Source dataset
uspto-grants-2012_07
Patent number
US08211901B2

Reaction notes

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